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Escitalopram, sold under the brand names Lexapro and Cipralex, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class by I Yalcin 2024 Cited by 86This study investigated the role of the noradrenergic system in the antidepressant-like effects of tramadol and desipramine in the unpredictable chronic mild channels in the antidepressant of tramadol in the mouse forced swimming test. Eur. J. Pharmacol 613(1-3), (2024). 89. Szkutnik-Fiedler D, Kus K Depression is a multifactorial disease, commonly occurring due to deficit of norepinephrine and serotonin. Tramadol, a weak µ opioid agonist vgmet by I YALCIN 2024 Cited by 86Tramadol, which inhibits the reuptake of noradrenaline and serotonin, is effective in animal models of depression. Its antidepressant-like effects may be by V Tayal Cited by 27Results: Tramadol produced significant antidepressant effect at all the doses, as indicated by reduction in immobility times as compared to Combining it with other serotonin norad-active drugs like antidepressants leads to a double whammy; Patients with little metabolism to M1 take As an opioid and central nervous system depressant, Tramadol does have the potential to slow down brain activity. This might cause feelings of
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